RESUMO
OBJECTIVE: To study the relationship between cervical length measured by ultrasound and risk of preterm delivery. METHODS: We measured cervical length in 2351 women between the 18th and 22nd week of pregnancy. Preterm delivery was categorized as before 37 weeks, before 34 weeks, and before 30 weeks. RESULTS: Before the 37th week, the odds ratios (ORs) of spontaneous delivery for cervical lengths in the 3rd, 5th, and 10th percentiles were, respectively, 25.47 (95% confidence intervals [CI], 15.5-41.73); 16.98 (95% CI, 11.51-25.05); and 7.55 (95% CI, 5.44-10.5). Before the 34th week the ORs were 28.7 (95% CI, 14.54-41.73); 20.5 (95% CI, 11.51-25.05); and 10.3 (95% CI, 5.44-10.5). And before the 30th week they were 29.8 (95% CI, 15.54-41.73); 23.1 (95% CI, 11.51-25.05); and 19.1 (95% CI, 7.44-31.5). In predicting premature delivery, the sensitivity, specificity, positive predictive value, and negative predictive value of cervical length were 26%, 98%, 63.6%, and 93.57% for the 3rd percentile; 34%, 97%, 51%, and 94% for the 5th percentile; and 39%, 92%, 31%, and 94% for the 10th percentile. CONCLUSION: Transvaginal measurement of cervical length during routine fetal morphological examination between the 18th and 22nd week of pregnancy helps identify asymptomatic women at risk for preterm delivery.
Assuntos
Colo do Útero/diagnóstico por imagem , Trabalho de Parto Prematuro/diagnóstico por imagem , Ultrassonografia Pré-Natal/métodos , Adulto , Medida do Comprimento Cervical/métodos , Feminino , Idade Gestacional , Humanos , Valor Preditivo dos Testes , Gravidez , Estudos Prospectivos , Fatores de Risco , Sensibilidade e Especificidade , Espanha , Adulto JovemRESUMO
The femoral hypoplasia - unusual facies syndrome is a rare disorder, which was described first three decades ago. It is characterised by the occurrence of short femurs with certain associated alterations mainly affecting the face, of which micrognathia is the most frequently found. Although the etiology of this condition is unknown, clear relationship with maternal insulin-dependent diabetes has often been reported, which suggests some sort of inherited component. Nevertheless, most cases occur sporadically. This entity is usually diagnosed after birth because prenatal ultrasound detection is rather difficult. Here, we report a case of prospective detection. So far, such cases have been seldom described in the literature.
Assuntos
Fácies , Fêmur/anormalidades , Ultrassonografia Pré-Natal/métodos , Anormalidades Múltiplas/diagnóstico por imagem , Adulto , Feminino , Fêmur/diagnóstico por imagem , Humanos , Masculino , Gravidez , SíndromeAssuntos
Doenças Fetais/etiologia , Hemorragias Intracranianas/etiologia , Papiloma do Plexo Corióideo/complicações , Adulto , Feminino , Doenças Fetais/diagnóstico por imagem , Humanos , Recém-Nascido , Doenças do Recém-Nascido/diagnóstico por imagem , Doenças do Recém-Nascido/etiologia , Hemorragias Intracranianas/diagnóstico por imagem , Imageamento por Ressonância Magnética , Masculino , Papiloma do Plexo Corióideo/diagnóstico por imagem , Gravidez , Ultrassonografia Pré-NatalAssuntos
Acrocefalossindactilia/diagnóstico por imagem , Imageamento Tridimensional/métodos , Acrocefalossindactilia/diagnóstico , Acrocefalossindactilia/genética , Adulto , Feminino , Humanos , Recém-Nascido , Mutação , Gravidez , Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética , Ultrassonografia Pré-NatalRESUMO
Neu-Laxova syndrome is a rare group of congenital malformations including intrauterine growth retardation (IUGR), microcephaly, central nervous system alterations, facial abnormalities, ichthyosis, limb abnormalities, generalized edema, polyhydramnios, and perinatal death. Thirty cases have been identified since the publication of the first two cases and only five of them had a prenatal diagnosis. The earliest diagnosis in a published case was at week 32 of gestation. This study illustrates that the detection of the syndrome during the second trimester of gestation is possible, with emphasis on the detection of the early appearance of polyhydramnios and the association of the syndrome with the Arabic ethnic group.